SCHEMBL19856028

SCHEMBL19856028

C=CC(=O)NCc1ccc(-c2ccc(CCCCC)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.62
THRA P10827 6/20 0.62
TGM2 P21980 1/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
RARB P10826 6/20 0.54
ALDH1A1 P00352 1/20 0.52
RARA P10276 1/20 0.52
MAPT P10636 1/20 0.52
MTOR P42345 1/20 0.52
S1PR1 P21453 2/20 0.49
S1PR3 Q99500 2/20 0.49
S1PR2 O95136 1/20 0.49
LPAR2 Q9HBW0 1/20 0.49
SPHK1 Q9NYA1 1/20 0.49
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370593 0.89 THRB (0.62) THRBTHRATGM2MEN1KMT2A
SCHEMBL20370416 0.89 THRB (0.62) THRBTHRATGM2MEN1KMT2A
SCHEMBL20370473 0.89 THRB (0.62) THRBTHRATGM2MEN1KMT2A
SCHEMBL19856026 0.89 THRB (0.62) THRBTHRATGM2MEN1KMT2A
SCHEMBL19855850 0.83 THRB (0.89) THRBTHRATGM2MEN1KMT2A
SCHEMBL19854545 0.82 THRB (0.69) THRBTHRATGM2MEN1KMT2A
SCHEMBL19856044 0.81 THRB (0.55) THRBTHRATGM2MEN1KMT2A
SCHEMBL19854537 0.81 THRB (0.62) THRBTHRATGM2MEN1KMT2A
SCHEMBL19855932 0.80 THRB (0.52) THRBTHRATGM2MEN1KMT2A
SCHEMBL732934 0.79 TGM2 (0.81) TGM2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885TGM2 4006/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 THRB 3939/4885THRA 3929/4885TGM2 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.