SCHEMBL19856034

SCHEMBL19856034

C=CC(=O)NCCCc1ccc(C2CCC(CCCCC)CC2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ZDHHC20 Q5W0Z9 1/20 0.41
▸ ZDHHC2 Q9UIJ5 1/20 0.41
▸ GAA P10253 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.36
▸ CNR2 P34972 4/20 0.34
▸ CNR1 P21554 3/20 0.34
▸ ASAH1 Q13510 1/20 0.34
▸ ITK Q08881 1/20 0.34
▸ DGAT1 O75907 1/20 0.34
▸ KMT2A Q03164 1/20 0.33
▸ THRA P10827 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ BTK Q06187 2/20 0.33
▸ TGM2 P21980 1/20 0.33
▸ SPHK1 Q9NYA1 1/20 0.33
▸ BMX P51813 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854956 0.93 ZDHHC20 (0.36) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19854967 0.89 DGAT1 (0.40) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19856042 0.87 ZDHHC20 (0.39) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL20370557 0.85 ZDHHC20 (0.41) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19854520 0.85 SPHK1 (0.47) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19855136 0.84 DGAT1 (0.40) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19853800 0.84 SPHK1 (0.47) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL20370484 0.84 SPHK1 (0.47) ZDHHC20ZDHHC2GAAALDH1A1LMNA
SCHEMBL19856012 0.84 SPHK1 (0.49) ZDHHC20ZDHHC2GAAKMT2ATHRA
SCHEMBL19854012 0.83 OPRL1 (0.39) ZDHHC20ZDHHC2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 ZDHHC20 946/4885ZDHHC2 1841/4885GAA 4879/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 ZDHHC20 946/4885ZDHHC2 1841/4885GAA 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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