SCHEMBL19856496

SCHEMBL19856496

CO[Si](OC)(OC)c1ccc2c(ccc3ccccc32)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP1B1 Q16678 2/20 0.48
HIF1A Q16665 2/20 0.48
HPRT1 P00492 3/20 0.46
TSHR P16473 2/20 0.44
CYP2A6 P11509 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 4/20 0.43
CYP1A2 P05177 3/20 0.43
HPGD P15428 3/20 0.43
CYP1A1 P04798 1/20 0.43
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
POLB P06746 1/20 0.37
CYP3A4 P08684 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895563 0.91 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL19856494 0.91 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL1470755 0.84 CYP2A6 (0.50) ALDH1A1HSD17B10CYP2A6TDP1MAPT
SCHEMBL29895592 0.84 CYP2A6 (0.50) ALDH1A1HSD17B10CYP2A6TDP1MAPT
SCHEMBL14092875 0.84 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL28254116 0.84 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL2352248 0.82 CYP2A6 (0.43) ALDH1A1HSD17B10HIF1ACYP2A6TDP1
SCHEMBL6746638 0.82 CYP2A6 (0.43) ALDH1A1HSD17B10HIF1ACYP2A6TDP1
SCHEMBL6748725 0.80 ALDH1A1 (0.41) ALDH1A1HPRT1MAPTCYP1A2HPGD
SCHEMBL12278167 0.77 HPRT1 (0.56) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025047282-A1 OPTICAL WAVEGUIDE AND METHOD FOR MANUFACTURING OPTICAL WAVEGUIDE 日産化学株式会社 2025-03-06 WO disclosed
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
WO-2022211070-A1 REACTIVE SILSESQUIOXANE COMPOUND-CONTAINING POLYMERIZABLE COMPOSITION FOR OPTICAL WAVEGUIDE 日産化学株式会社 2022-10-06 WO disclosed
CN-109154677-B Low viscosity agent for high refractive index polymerizable compound and polymerizable composition containing same 日产化学株式会社 2022-07-05 CN disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
EP-3345943-B1 POLYMERIZABLE COMPOSITION COMPRISING SILSESQUIOXANE COMPOUND HAVING ACRYLIC GROUP NISSAN CHEMICAL CORP (JP) 2021-06-23 EP disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
US-10894800-B2 Polymerizable silane compound NISSAN CHEMICAL CORPORATION (JP) 2021-01-19 US disclosed
EP-3466956-B1 POLYMERIZABLE SILANE COMPOUND NISSAN CHEMICAL CORP (JP) 2020-12-09 EP disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
US-20190169345-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING NISSAN CHEMICAL CORPORATION (JP) 2019-06-06 US disclosed
EP-3327049-B1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND NISSAN CHEMICAL CORP (JP) 2019-05-29 EP disclosed
EP-3466956-A1 POLYMERIZABLE SILANE COMPOUND Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
EP-3466994-A1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
EP-3444284-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING Nissan Chemical Corporation (JP) 2019-02-20 EP disclosed
US-20180244852-A1 POLYMERIZABLE COMPOSITION COMPRISING SILSESQUIOXANE COMPOUND HAVING ACRYLIC GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-30 US disclosed
EP-3345943-A1 POLYMERIZABLE COMPOSITION COMPRISING SILSESQUIOXANE COMPOUND HAVING ACRYLIC GROUP Nissan Chemical Industries, Ltd. (JP) 2018-07-11 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894800-B2 Polymerizable silane compound PCNA, ARL1, CCNE1 ALDH1A1 958/4885HSD17B10 2684/4885CYP1B1 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.