SCHEMBL2352248

SCHEMBL2352248

CO[Si](OC)(OC)c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.43
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 5/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
HBB P68871 1/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NQO1 P15559 1/20 0.38
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.34
GLA P06280 1/20 0.34
ACHE P22303 1/20 0.34
NQO2 P16083 5/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746638 1.00 CYP2A6 (0.43) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL1470755 0.94 CYP2A6 (0.50) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL29895592 0.94 CYP2A6 (0.50) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL13942780 0.83 PDGFRB (0.50) CYP1A2ALDH1A1CYP3A4ALOX15CASP1
SCHEMBL19856496 0.82 ALDH1A1 (0.48) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL14092875 0.82 ALDH1A1 (0.40) CYP1A2ALDH1A1CYP3A4HIF1AHSD17B10
SCHEMBL6746757 0.82 CYP2A6 (0.42) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL29895563 0.80 ALDH1A1 (0.50) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL19856494 0.80 ALDH1A1 (0.50) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4
SCHEMBL15066858 0.79 CYP2A6 (0.48) CYP2A6CYP1A2ALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same TORAY INDUSTRIES, INC. (JP) 2023-10-24 US disclosed
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN disclosed
EP-3381969-B1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES (JP) 2020-06-03 EP disclosed
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES, INC. (JP) 2018-11-15 US disclosed
EP-3381969-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME Toray Industries, Inc. (JP) 2018-10-03 EP disclosed
US-8513372-B2 Asymmetric photo-patternable sol-gel precursors and their methods of preparation NITTO DENKO CORPORATION (JP) 2013-08-20 US disclosed
US-20110207049-A1 ASYMMETRIC PHOTO-PATTERNABLE SOL-GEL PRECURSORS AND THEIR METHODS OF PREPARATION Nito Denko Corporation (JP) 2011-08-25 US disclosed
WO-2010053629-A1 ASYMMETRIC PHOTO-PATTERNABLE SOL-GEL PRECURSORS AND THEIR METHODS OF PREPARATION NITTO DENKO CORPORATION (JP) 2010-05-14 WO disclosed
US-20090246716-A1 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE NITTO DENKO CORPORATION (JP) 2009-10-01 US disclosed
WO-2009120410-A2 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE NITTO DENKO CORPORATION (JP) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207049-A1 ASYMMETRIC PHOTO-PATTERNABLE SOL-GEL PRECURSORS AND THEIR METHODS OF PREPARATION CRY1, CRY2, SOS2 CYP2A6 3311/4885CYP1A2 4117/4885ALDH1A1 3638/4885
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same ASH2L, SETDB1, BMI1 CYP2A6 1842/4885CYP1A2 974/4885ALDH1A1 2743/4885
US-20090246716-A1 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE SOS1, SOS2, MMS19 CYP2A6 3977/4885CYP1A2 4334/4885ALDH1A1 2390/4885
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME ASH2L, SETDB1, BMI1 CYP2A6 1842/4885CYP1A2 974/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.