SCHEMBL19856498

SCHEMBL19856498

C=C(C)c1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35399 0.85
SCHEMBL9516265 0.85 MAPT (0.44) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL455038 0.77 HSD17B1 (0.61) HSD17B1MAPTSMN1; SMN2
SCHEMBL56361 0.77 MAPT (0.40) MAPTSMN1; SMN2HSD17B10
SCHEMBL9514759 0.76 HSD17B1 (0.60) HSD17B1MAPTSMN1; SMN2HSD17B10
SCHEMBL4502407 0.76 SMN1; SMN2 (0.60) MAPTSMN1; SMN2
SCHEMBL23268269 0.74 HSD17B1 (0.37) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL10583063 0.74 CYP3A4 (0.52) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL21133359 0.74 HSD17B1 (0.37) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL22991441 0.74 TPMT (0.41) HSD17B1MAPTSMN1; SMN2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
US-10894800-B2 Polymerizable silane compound NISSAN CHEMICAL CORPORATION (JP) 2021-01-19 US disclosed
EP-3466956-B1 POLYMERIZABLE SILANE COMPOUND NISSAN CHEMICAL CORP (JP) 2020-12-09 EP disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
EP-3466994-B1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORP (JP) 2020-09-16 EP disclosed
US-20200148875-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2020-05-14 US disclosed
EP-3373051-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-11 EP disclosed
EP-3617758-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Corporation (JP) 2020-03-04 EP disclosed
EP-3466956-A1 POLYMERIZABLE SILANE COMPOUND Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
EP-3466994-A1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
US-10253126-B2 Optical waveguide-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
EP-3444284-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING Nissan Chemical Corporation (JP) 2019-02-20 EP disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894800-B2 Polymerizable silane compound PCNA, ARL1, CCNE1 HSD17B1 1061/4885MAPT 1893/4885SMN1; SMN2 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.