SCHEMBL21133359

SCHEMBL21133359

C=C(C)c1ccc(-c2ccc(C(=C)Cl)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ RXRA P19793 2/20 0.33
▸ RXRB P28702 2/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.31
▸ CLK1 P49759 1/20 0.30
▸ CLK2 P49760 1/20 0.30
▸ DYRK1A Q13627 1/20 0.30
▸ HIPK1 Q86Z02 1/20 0.30
▸ HIPK2 Q9H2X6 1/20 0.30
▸ HIPK3 Q9H422 1/20 0.30
▸ CLK4 Q9HAZ1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12449039 0.93 KMT2A (0.32) MAPTHSD17B10
SCHEMBL9516265 0.87 MAPT (0.44) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL25057395 0.82 MAPT (0.59) HSD17B1MAPTSMN1; SMN2
SCHEMBL25955317 0.82 SMN1; SMN2 (0.43) HSD17B1MAPTSMN1; SMN2RXRARXRB
SCHEMBL56361 0.79 MAPT (0.40) MAPTSMN1; SMN2HSD17B10
SCHEMBL13285771 0.79 MAPT (0.40) MAPTHSD17B10
SCHEMBL4502407 0.78 SMN1; SMN2 (0.60) MAPTSMN1; SMN2
SCHEMBL9514759 0.78 HSD17B1 (0.60) HSD17B1MAPTSMN1; SMN2HSD17B10
SCHEMBL19228099 0.78 SMN1; SMN2 (0.48) MAPTSMN1; SMN2
SCHEMBL5033205 0.77 ALDH1A1 (0.48) HSD17B1SMN1; SMN2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4141053-A1 POLYAMIDE-BASED FILM, METHOD OF PREPARING THE SAME, AND COVER WINDOW AND DISPLAY DEVICE COMPRISING THE SAME SKC Co., Ltd. (KR) 2023-03-01 — — EP disclosed
EP-3521338-A1 POLYAMIDE-IMIDE FILM AND PREPARATION METHOD THEREOF SKC Co., Ltd. (KR) 2019-08-07 — — EP disclosed
EP-3505558-A1 PROCESS FOR PREPARING A POLY(AMIDE-IMIDE) FILM AND A POLY(AMIDE-IMIDE) FILM PREPARED BY THE SAME SKC Co., Ltd. (KR) 2019-07-03 — — EP disclosed
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