Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | PLD2 | O14939 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856903 | 1.00 | STAT6 (0.38) | STAT6CYP51A1SMYD3PYGLPLD1 | |
| SCHEMBL19857011 | 0.88 | SMYD3 (0.37) | STAT6CYP51A1SMYD3DRD1DRD4 | |
| SCHEMBL4344872 | 0.87 | SMYD3 (0.37) | STAT6CYP51A1SMYD3PYGLPYGM | |
| SCHEMBL4343724 | 0.86 | CYP51A1 (0.36) | STAT6CYP51A1SMYD3PYGLPYGM | |
| SCHEMBL4343721 | 0.83 | TDP1 (0.36) | STAT6CYP51A1SMYD3PYGLBCAT1 | |
| SCHEMBL4341332 | 0.83 | HTRA1 (0.36) | STAT6CYP51A1SMYD3PYGLDRD3 | |
| SCHEMBL19856915 | 0.83 | TDP1 (0.36) | STAT6CYP51A1SMYD3PYGLBCAT1 | |
| SCHEMBL4335350 | 0.83 | TDP1 (0.36) | STAT6CYP51A1SMYD3PYGLBCAT1 | |
| SCHEMBL19856965 | 0.83 | TDP1 (0.36) | STAT6CYP51A1SMYD3PYGLBCAT1 | |
| SCHEMBL4350449 | 0.83 | HTRA1 (0.36) | STAT6CYP51A1SMYD3PYGLDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |