Pyrogallol

Pyrogallol

SCHEMBL19857036

CCCC(=O)O.Oc1cccc(O)c1O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 7/20 0.56
FFAR3 O14843 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
ALDH1A1 P00352 2/20 0.50
ADAMTS4 O75173 1/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
FYN P06241 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
MMP8 P22894 1/20 0.50
CA6 P23280 1/20 0.50
CDK2 P24941 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL28191561 0.87 HDAC3 (0.59) IAPPFFAR3HDAC3HDAC1HDAC2
Pyrogallol SCHEMBL8879563 0.86 AKR1B1 (0.59) IAPPALDH1A1ALOX15HSD17B10TDP1
Stearic Acid SCHEMBL9177740 0.85 ALDH1A1 (0.62) ALDH1A1ALOX15HSD17B10TDP1MEN1
1-Naphthol SCHEMBL9450887 0.81 CYP1A2 (0.61) IAPPFFAR3HDAC3HDAC1HDAC2
Stearic Acid SCHEMBL11133568 0.81 ALDH1A1 (0.57) ALDH1A1ALOX15HSD17B10TDP1MEN1
Orthocresol SCHEMBL1900384 0.80 FFAR3 (0.50) IAPPFFAR3HDAC3HDAC1HDAC2
Resorcinol SCHEMBL8461221 0.79 FFAR3 (0.54) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626727 0.79 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626724 0.79 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1994703 0.79 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3496773-B1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc (US) 2025-12-17 EP disclosed
EP-3496772-B1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Life Sciences Llc (US) 2025-11-26 EP disclosed
US-20230105383-A1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc 2023-04-06 US disclosed
US-11524096-B2 Wetting agent formulation TELEFLEX LIFE SCIENCES PTE. LTD. (SG) 2022-12-13 US disclosed
US-20190216985-A1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Life Sciences Llc 2019-07-18 US disclosed
EP-3496773-A1 WETTING AGENT FORMULATION Teleflex Lifesciences (BM) 2019-06-19 EP disclosed
EP-3496772-A1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Lifesciences (BM) 2019-06-19 EP disclosed
US-20190167849-A1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc 2019-06-06 US disclosed
WO-2018028831-A1 WETTING AGENT FORMULATION TELEFLEX LIFESCIENCES (BM) 2018-02-15 WO disclosed
WO-2018029279-A1 METHOD FOR STERILIZING A MEDICAL DEVICE TELEFLEX LIFESCIENCES (BM) 2018-02-15 WO disclosed
EP-3281649-A1 WETTING AGENT FORMULATION Teleflex Lifesciences (BM) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524096-B2 Wetting agent formulation CTSA, GLA, MGAM IAPP 3126/4885FFAR3 3541/4885HDAC3 852/4885
US-20230105383-A1 WETTING AGENT FORMULATION CTSA, GLA, CHIA IAPP 3065/4885FFAR3 3546/4885HDAC3 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.