Pyrogallol

Pyrogallol

SCHEMBL8879563

CCCCCC(=O)O.Oc1cccc(O)c1O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.59
ALDH1A1 P00352 3/20 0.59
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
HTT P42858 1/20 0.59
ATM Q13315 1/20 0.59
GPR84 Q9NQS5 7/20 0.57
PPARG P37231 7/20 0.57
PPARD Q03181 7/20 0.57
PPARA Q07869 7/20 0.57
HDAC11 Q96DB2 5/20 0.57
TSHR P16473 4/20 0.57
PTPN1 P18031 3/20 0.57
TLR2 O60603 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
FABP4 P15090 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
ESR1 P03372 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stearic Acid SCHEMBL9177740 0.98 ALDH1A1 (0.62) AKR1B1ALDH1A1KMT2AMEN1MAPT
Stearic Acid SCHEMBL11133568 0.93 ALDH1A1 (0.57) AKR1B1ALDH1A1KMT2AMEN1MAPT
Oleic Acid SCHEMBL8176589 0.89 PPARG (0.68) ALDH1A1KMT2AMAPTATMPPARG
2,3-Dihydroxybenzoic Acid SCHEMBL28180025 0.87 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1MAPTHTT
Octanoic Acid SCHEMBL9716530 0.87 GPR84 (0.65) AKR1B1ALDH1A1KMT2AMEN1MAPT
Stearic Acid SCHEMBL27415667 0.87 GPR84 (0.65) AKR1B1ALDH1A1KMT2AMEN1MAPT
Dodecanoate SCHEMBL27429957 0.87 GPR84 (0.65) AKR1B1ALDH1A1KMT2AMEN1MAPT
Palmitic Acid SCHEMBL27441228 0.87 GPR84 (0.65) AKR1B1ALDH1A1KMT2AMEN1MAPT
Pyrogallol SCHEMBL8879000 0.87 IAPP (0.68) ALDH1A1KMT2AMEN1MAPTHTT
Pyrogallol SCHEMBL19857036 0.86 IAPP (0.56) AKR1B1ALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618932-A Photoactive compounds and compositions SHIPLEY COMPANY, L.L.C. (US) 1997-04-08 US disclosed
US-5514515-A Photoactive compounds having a heterocyclic group used in photoresist compositions SHIPLEY COMPANY, L.L.C. (US) 1996-05-07 US disclosed