Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857041 | 0.86 | PPARD (0.45) | PPARDPPARASYKSCN5AS1PR1 | |
| SCHEMBL16824807 | 0.80 | FFAR4 (0.47) | PPARDFFAR4SCN5A | |
| SCHEMBL16821806 | 0.77 | S1PR1 (0.39) | PPARDFFAR1FFAR4SYKSCN5A | |
| SCHEMBL19857042 | 0.75 | PDE4A (0.45) | PPARDFFAR4SYKSCN5A | |
| SCHEMBL16821782 | 0.73 | SYK (0.36) | PPARDSYKSCN5AS1PR1 | |
| SCHEMBL16821772 | 0.73 | FFAR1 (0.37) | PPARDFFAR1FFAR4SCN5AS1PR1 | |
| SCHEMBL16821736 | 0.73 | SCN5A (0.38) | PPARDSYKSCN5AS1PR1 | |
| SCHEMBL5548424 | 0.72 | S1PR1 (0.53) | FFAR1FFAR4SCN5AS1PR1 | |
| SCHEMBL16821787 | 0.72 | GRM2 (0.37) | PPARDSCN5AS1PR1 | |
| SCHEMBL21508410 | 0.72 | SCN5A (0.43) | FFAR1FFAR4SCN5AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092234-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2018-02-14 | — | — | EP | disclosed |