Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857045 | 0.86 | PPARD (0.46) | PPARDSCN5AS1PR1PPARASYK | |
| SCHEMBL19857039 | 0.83 | SCN5A (0.46) | PPARDSCN5ACTSASYKSLC6A7 | |
| SCHEMBL19857042 | 0.80 | PDE4A (0.45) | PPARDSCN5ASYKDYRK1APDE4A | |
| SCHEMBL16821736 | 0.77 | SCN5A (0.38) | PPARDSCN5AS1PR1SYKDYRK1A | |
| SCHEMBL16821787 | 0.76 | GRM2 (0.37) | PPARDSCN5AS1PR1DYRK1A | |
| SCHEMBL19857043 | 0.75 | CTSA (0.51) | PPARDCTSASYKDYRK1APDE4A | |
| SCHEMBL16824800 | 0.73 | PDE4A (0.48) | SYKDYRK1APDE4APDE4BPDE4C | |
| SCHEMBL16821859 | 0.73 | SCN5A (0.35) | PPARDSCN5AS1PR1SYK | |
| SCHEMBL16821855 | 0.73 | GRM5 (0.42) | S1PR1CTSASYKSLC6A7DYRK1A | |
| SCHEMBL16821806 | 0.72 | S1PR1 (0.39) | PPARDSCN5AS1PR1SYKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092234-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2018-02-14 | — | — | EP | disclosed |