Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632228 | 0.92 | THRB (0.71) | THRBTHRA | |
| SCHEMBL19859387 | 0.92 | THRB (0.71) | THRBTHRA | |
| SCHEMBL24632224 | 0.92 | THRB (0.71) | THRBTHRA | |
| SCHEMBL21286649 | 0.89 | THRB (0.72) | THRBTHRA | |
| SCHEMBL21286682 | 0.89 | THRB (0.72) | THRBTHRA | |
| SCHEMBL19859414 | 0.88 | THRB (0.79) | THRBTHRA | |
| SCHEMBL19859392 | 0.87 | THRB (0.77) | THRBTHRA | |
| SCHEMBL29074251 | 0.87 | THRB (0.70) | THRBTHRA | |
| SCHEMBL19859380 | 0.86 | THRB (0.76) | THRBTHRA | |
| SCHEMBL19859391 | 0.85 | THRB (0.71) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325886-B2 | Amide compounds, pharmaceutical compositions thereof, and methods of using the same | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-05-10 | — | — | US | claimed |
| US-20210284599-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-09-16 | — | — | US | claimed |
| EP-3497077-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | Oregon Health & Science University (US) | 2019-06-19 | — | — | EP | claimed |
| CN-109843849-A | Amide compounds, pharmaceutical compositions thereof, and methods of use thereof | 俄勒冈健康科学大学 | 2019-06-04 | — | — | CN | claimed |
| WO-2018032012-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-02-15 | — | — | WO | claimed |
| CN-109843849-B | Amide compounds, pharmaceutical compositions thereof, and methods of use thereof | 俄勒冈健康科学大学 | 2023-09-22 | — | — | CN | disclosed |
| US-11325886-B2 | Amide compounds, pharmaceutical compositions thereof, and methods of using the same | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-05-10 | — | — | US | disclosed |
| US-11325886-B2 | Amide compounds, pharmaceutical compositions thereof, and methods of using the same | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-05-10 | — | — | US | disclosed |
| US-20210284599-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284599-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| EP-3497077-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | Oregon Health & Science University (US) | 2019-06-19 | — | — | EP | disclosed |
| WO-2018032012-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-02-15 | — | — | WO | disclosed |
| WO-2018032012-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284599-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | ACHE, IAPP, HTT | THRB 4654/4885THRA 4479/4885 |
| US-11325886-B2 | Amide compounds, pharmaceutical compositions thereof, and methods of using the same | ACHE, IAPP, HTT | THRB 4654/4885THRA 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.