Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859451 | 1.00 | CES2 (0.55) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL68050 | 0.87 | CES2 (0.69) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL9723456 | 0.87 | CES2 (0.69) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL30741457 | 0.87 | CES2 (0.69) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL68051 | 0.87 | CES2 (0.69) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL2480783 | 0.80 | CA1 (0.61) | CES2CES1MAPTKDM4EALDH1A1 | |
| SCHEMBL18972898 | 0.79 | CES2 (0.60) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL80442 | 0.79 | CES2 (0.60) | CES2CES1PTGS2MAPTCYP2C19 | |
| SCHEMBL28255793 | 0.79 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL28243502 | 0.79 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173217-B2 | Methods and compositions for near infrared fluorescent nanodots with aggregation-induced emission characteristics | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-11-16 | — | — | US | disclosed |
| WO-2018030957-A1 | METHODS AND COMPOSITIONS FOR NEAR INFRARED FLUORESCENT NANODOTS WITH AGGREGATION-INDUCED EMISSION CHARACTERISTICS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2018-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173217-B2 | Methods and compositions for near infrared fluorescent nanodots with aggregation-induced emission characteristics | HCCS, CD63, TP53 | CES2 2450/4885CES1 2674/4885PTGS2 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.