Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.69 |
| ▸ | CES1 | P23141 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68051 | 1.00 | CES2 (0.69) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL30741457 | 1.00 | CES2 (0.69) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL68050 | 1.00 | CES2 (0.69) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL28243502 | 0.92 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL80442 | 0.92 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL28255793 | 0.92 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL18972898 | 0.92 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL25525846 | 0.92 | CES2 (0.60) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL2957320 | 0.90 | ALDH1A1 (0.70) | CES2CES1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL18972614 | 0.90 | CES2 (0.58) | CES2CES1MAPTCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108070-A1 | LUMINOGENS FOR BIOLOGICAL APPLICATIONS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-06-21 | — | — | WO | disclosed |
| EP-0467847-A1 | Polyarylene ether with tetraphenylethylene units | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |