Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16698251 | 1.00 | HSD11B1 (0.48) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL160953 | 1.00 | HSD11B1 (0.48) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL28134791 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL27917064 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL15772802 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL28134798 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL3051989 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL28134787 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL31349739 | 0.97 | HSD11B1 (0.46) | HSD11B1CYP2C9POLBTDP1HSD17B10 | |
| SCHEMBL29099215 | 0.84 | POLB (0.43) | POLBTDP1TSHRAPEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-05-11 | — | — | US | disclosed |
| US-9890192-B2 | Targeted nitroxide agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | HSD11B1 2734/4885CYP2C9 908/4885POLB 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.