Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | FABP1 | P07148 | 1/20 | 0.61 |
| ▸ | FABP6 | P51161 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12042470 | 0.90 | MEN1 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12058759 | 0.87 | KMT2A (0.75) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8925693 | 0.85 | ALDH1A1 (0.75) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13959022 | 0.83 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL94838 | 0.82 | MEN1 (0.72) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13973332 | 0.82 | MEN1 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5600177 | 0.79 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8916560 | 0.78 | MEN1 (0.72) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13417633 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1LMNAFABP1 | |
| SCHEMBL8917255 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890123-B2 | 6-aminoisoquinoline compounds | AERIE PHARMACEUTICALS, INC. (US) | 2018-02-13 | — | — | US | disclosed |