Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342814 | 0.81 | REN (0.56) | RENAGTR2ACE2 | |
| SCHEMBL27673678 | 0.80 | REN (0.65) | REN | |
| SCHEMBL27335661 | 0.80 | REN (0.65) | REN | |
| Triletide SCHEMBL27342203 | 0.80 | REN (0.68) | RENACE2 | |
| Triletide SCHEMBL29387766 | 0.80 | REN (0.68) | RENACE2 | |
| Triletide SCHEMBL29403076 | 0.80 | REN (0.68) | RENACE2 | |
| SCHEMBL7317825 | 0.80 | REN (0.66) | REN | |
| SCHEMBL28042599 | 0.79 | REN (0.61) | RENAGTR2ACE2SLC15A2 | |
| Hydrochloric Acid SCHEMBL27341574 | 0.78 | REN (0.62) | REN | |
| SCHEMBL27343925 | 0.78 | MME (0.61) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889213-B2 | Multimodal imaging of fibrin | THE GENERAL HOSPITAL CORPORATION (US) | 2018-02-13 | — | — | US | disclosed |