SCHEMBL19860903

CNC(=O)CCCCC(=O)N(CC(=O)NCCO[C@@H]1O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O)CC(=O)NCCO[C@H]1OC(CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](O)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CD209	Q9NNX6	2/20	0.42

▸	FGF1	P05230	4/20	0.40

▸	VEGFA	P15692	4/20	0.40

▸	MMP13	P45452	2/20	0.40

▸	SELP	P16109	2/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	CYP3A4	P08684	1/20	0.39

▸	ALOX15	P16050	1/20	0.39

▸	MAPK1	P28482	1/20	0.39

▸	HSD17B10	Q99714	1/20	0.39

▸	FGF2	P09038	1/20	0.39

▸	HPSE	Q9Y251	1/20	0.39

▸	MDK	P21741	1/20	0.38

▸	LGALS8	O00214	2/20	0.37

▸	LGALS3	P17931	2/20	0.37

▸	LGALS4	P56470	2/20	0.37

▸	SELE	P16581	2/20	0.37

▸	ENGASE	Q8NFI3	1/20	0.37

▸	SELL	P14151	1/20	0.37

▸	GJB2	P29033	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19860868	1.00	CD209 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL18161289	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL16640822	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL16640814	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL16644871	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL18056139	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL16644897	0.93	FGF1 (0.42)	CD209FGF1VEGFAMMP13SELP
SCHEMBL16628168	0.91	MMP13 (0.46)	CD209FGF1VEGFAMMP13SELP
SCHEMBL19860816	0.91	MMP13 (0.46)	CD209FGF1VEGFAMMP13SELP
SCHEMBL23316924	0.90	CD209 (0.40)	CD209FGF1VEGFAMMP13SELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9889205-B2	Glucose-responsive insulin conjugates	MERCK SHARP & DOHME CORP. (US)	2018-02-13	—	—	US	disclosed