Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991001 | 0.82 | KDM4E (0.42) | KDM4EPIK3C2BALDH1A1HSD17B10MEN1 | |
| SCHEMBL16922688 | 0.79 | KDM4E (0.55) | KDM4EPIK3C2BALDH1A1HSD17B10MEN1 | |
| SCHEMBL28123984 | 0.79 | PRKDC (0.48) | KDM4EALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL22657488 | 0.78 | AKR1C3 (0.42) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27410032 | 0.78 | MYC (0.43) | KDM4EPIK3C2BALDH1A1HSD17B10MEN1 | |
| SCHEMBL12831239 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28991680 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20467558 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2376896 | 0.76 | LGMN (0.49) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22996752 | 0.75 | KDM4E (0.50) | KDM4EPIK3C2BALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220741-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | DICE MOLECULES SV, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-9890119-B2 | Indole and azaindole derivative having AMPK-activating activity | SHIONOGI & CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |