SCHEMBL19861099

SCHEMBL19861099

c1ccc(-c2ccc(Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.47
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CALM1 P0DP23 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13884022 1.00 TAAR1 (0.47) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL10204137 1.00 TAAR1 (0.47) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL13884024 0.98 TAAR1 (0.48) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL14106795 0.98 ALDH1A1 (0.48) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL13884013 0.98 ALDH1A1 (0.48) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL21438016 0.98 ALDH1A1 (0.48) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL16298981 0.96 CALM1 (0.52) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL9768685 0.91 CALM1 (0.55) ALDH1A1CYP3A4TDP1L3MBTL1KDM4E
SCHEMBL14018354 0.91 CALM1 (0.55) ALDH1A1CYP3A4TDP1L3MBTL1KDM4E
SCHEMBL17321134 0.91 CYP2C19 (0.46) TAAR1ALDH1A1CYP3A4TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9892817-B2 Conductive composition, and conductive complex NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-13 US disclosed