Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18737015 | 0.94 | CHRM4 (0.44) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL13974063 | 0.86 | HRH3 (0.50) | SIGMAR1 | |
| SCHEMBL19573431 | 0.85 | RAB9A (0.38) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL21016307 | 0.85 | ALDH1A1 (0.38) | PAOXUSP2ALDH1A1HPGD | |
| SCHEMBL22877714 | 0.84 | HRH3 (0.54) | SIGMAR1 | |
| SCHEMBL22877833 | 0.82 | CXCR4 (0.48) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20076261 | 0.82 | KDM1A (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL26455630 | 0.81 | PAOX (0.47) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL14294342 | 0.81 | PAOX (0.47) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL19861321 | 0.81 | SMN1; SMN2 (0.47) | SIGMAR1CHRM2CHRM1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |