Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861534 | 1.00 | MEN1 (0.39) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL20076517 | 0.95 | MEN1 (0.40) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL19861353 | 0.89 | LMNA (0.36) | LMNACYP4F2CYP4A11GAA | |
| SCHEMBL19861450 | 0.86 | LMNA (0.39) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL20076506 | 0.86 | LMNA (0.39) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL1101306 | 0.81 | LMNA (0.57) | MEN1KMT2AMAPTATMLMNA | |
| SCHEMBL19861341 | 0.79 | GAA (0.35) | L3MBTL1CYP4F2CYP4A11GAA | |
| SCHEMBL20076321 | 0.79 | GAA (0.35) | L3MBTL1CYP4F2CYP4A11GAA | |
| SCHEMBL15183604 | 0.78 | ALDH1A1 (0.39) | KMT2AL3MBTL1CYP4F2CYP4A11HTT | |
| SCHEMBL15183610 | 0.78 | ALDH1A1 (0.39) | KMT2AL3MBTL1CYP4F2CYP4A11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |