Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861667 | 0.76 | KISS1R (0.32) | KISS1R | |
| SCHEMBL19861659 | 0.74 | KISS1R (0.33) | KISS1R | |
| SCHEMBL2736114 | 0.73 | — | — | |
| SCHEMBL13233640 | 0.73 | USP2 (0.33) | KISS1RCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14865512 | 0.71 | KISS1R (0.46) | KISS1R | |
| SCHEMBL31170245 | 0.69 | KISS1R (0.37) | KISS1RCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL1829813 | 0.67 | KISS1R (0.37) | KISS1RCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL3830282 | 0.67 | KISS1R (0.37) | KISS1RCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL12233190 | 0.67 | CHRM2 (0.37) | — | |
| SCHEMBL3687647 | 0.66 | PRMT3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891239-B2 | Modulators of pharmacokinetic properties of therapeutics | GILEAD SCIENCES, INC. (US) | 2018-02-13 | — | — | US | disclosed |