Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492439 | 0.76 | FAAH (0.32) | — | |
| SCHEMBL21778945 | 0.75 | — | — | |
| SCHEMBL21233403 | 0.74 | — | — | |
| SCHEMBL19155331 | 0.73 | FAAH (0.31) | — | |
| SCHEMBL18391368 | 0.70 | — | — | |
| SCHEMBL20078814 | 0.68 | HTT (0.42) | LMNAMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL18925131 | 0.68 | — | — | |
| SCHEMBL21787565 | 0.67 | SLC5A2 (0.36) | NISCHKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20662320 | 0.65 | NISCH (0.32) | NISCHKDM4EALDH1A1HSD17B10 | |
| SCHEMBL19492664 | 0.64 | HDAC4 (0.43) | MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889082-B2 | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-13 | — | — | US | disclosed |