SCHEMBL21787565

SCHEMBL21787565

c1ccc2c(c1)OC(c1ccc3c(c1)SCO3)O2

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 1/20 0.36
NISCH Q9Y2I1 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CTNNB1 P35222 1/20 0.31
WNT3A P56704 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20662320 0.87 NISCH (0.32) NISCHNPC1RAB9AKDM4EALDH1A1
SCHEMBL21076187 0.80 LMNA (0.34) NPC1RAB9AKDM4EALDH1A1HSD17B10
SCHEMBL22221997 0.74 CTNNB1 (0.38) SLC5A2CTNNB1WNT3A
SCHEMBL19492456 0.74 CTNNB1 (0.38) SLC5A2CTNNB1WNT3A
SCHEMBL57996 0.72
SCHEMBL29395105 0.72
SCHEMBL20759067 0.70 RAB9A (0.38) NPC1RAB9AKDM4EHSD17B10
SCHEMBL18839045 0.68 LTA4H (0.46) NPC1RAB9ACTNNB1WNT3ALTA4H
SCHEMBL18838084 0.67 KDM4E (0.35) SLC5A2NPC1KDM4EALDH1A1HSD17B10
SCHEMBL19861633 0.67 NISCH (0.31) NISCHKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001570-B2 6-amino-quinolinone compounds and derivatives as BCL6 inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-05-11 US disclosed
US-20200071297-A1 NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2020-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200071297-A1 NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS BCL6, BCL6B, BCOR SLC5A2 2629/4885NISCH 4598/4885NPC1 1516/4885
US-11001570-B2 6-amino-quinolinone compounds and derivatives as BCL6 inhibitors BCL6, BCL6B, BCOR SLC5A2 2265/4885NISCH 4579/4885NPC1 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.