Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861964 | 1.00 | SIRT1 (0.51) | SIRT1SIRT2FOLH1MAPTKLK7 | |
| SCHEMBL19862012 | 1.00 | SIRT1 (0.51) | SIRT1SIRT2FOLH1MAPTKLK7 | |
| SCHEMBL19861961 | 0.94 | SIRT2 (0.51) | SIRT1SIRT2MAPTKLK7KLK5 | |
| SCHEMBL21062308 | 0.94 | PTGER4 (0.52) | SIRT1SIRT2MAPTKLK7KLK5 | |
| SCHEMBL21062306 | 0.94 | PTGER4 (0.52) | SIRT1SIRT2MAPTKLK7KLK5 | |
| SCHEMBL19861963 | 0.91 | CTSL (0.54) | SIRT1SIRT2KLK7KLK5 | |
| SCHEMBL19862013 | 0.91 | CTSL (0.54) | SIRT1SIRT2KLK7KLK5 | |
| SCHEMBL29313375 | 0.91 | SIRT2 (0.49) | SIRT1SIRT2MAPTKLK7KLK5 | |
| SCHEMBL30241791 | 0.91 | MAPT (0.49) | SIRT1SIRT2MAPTKLK7KLK5 | |
| SCHEMBL17039853 | 0.90 | FOLH1 (0.57) | SIRT1SIRT2FOLH1MAPTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037414-B2 | Processes for preparing pharmaceutically relevant peptides | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-10633415-B2 | Processes for preparing pharmaceutically relevant peptides | STEALTH BIOTHERAPEUTICS CORP (MC) | 2020-04-28 | — | — | US | disclosed |
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2018-02-15 | — | — | US | disclosed |
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | ADM2, VIP, PEPD | SIRT1 4025/4885SIRT2 3395/4885FOLH1 237/4885 |
| US-10633415-B2 | Processes for preparing pharmaceutically relevant peptides | ADM2, VIP, PEPD | SIRT1 4025/4885SIRT2 3395/4885FOLH1 237/4885 |
| US-12037414-B2 | Processes for preparing pharmaceutically relevant peptides | ADM2, VIP, PEPD | SIRT1 4025/4885SIRT2 3395/4885FOLH1 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.