SCHEMBL19862370

SCHEMBL19862370

Cc1ccc2c(c1)C1(c3cc(Br)ccc3C=C2)c2ccccc2-c2c1ccc1oc3ccccc3c21

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862357 0.92 GABRP (0.31)
SCHEMBL20224556 0.90 PDK2 (0.33) CSNK2A2CSNK2BCSNK2A1MAOAMAOB
SCHEMBL18034352 0.84 PDK2 (0.38) MAOAMAOBTP53CYP3A4MAPT
SCHEMBL18034420 0.84 PDK2 (0.38) MAOAMAOBTP53CYP3A4MAPT
SCHEMBL18034445 0.84 PDK2 (0.38) MAPT
SCHEMBL18034339 0.84 PDK2 (0.38) MAPT
SCHEMBL22930716 0.82 PDK2 (0.37) MAOAMAOBTP53CYP3A4MAPT
SCHEMBL19395176 0.82 PDK2 (0.37) MAPT
SCHEMBL19395172 0.82 PDK2 (0.37) MAPT
SCHEMBL16491688 0.82 NMUR2 (0.36) MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ORC3, AOX1, RCOR3 CSNK2A2 2755/4885CSNK2B 2443/4885CSNK2A1 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.