SCHEMBL19862390

SCHEMBL19862390

CC1(C)OB(c2ccc3c(c2)C2(c4ccccc4C=C3)c3ccccc3-c3c2ccc2sc4ccccc4c32)OC1(C)C

nearest known ligand 0.31

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
DUSP3 P51452 1/20 0.30
BLM P54132 1/20 0.30
PTPN5 P54829 1/20 0.30
KMT2A Q03164 1/20 0.30
PTPN11 Q06124 1/20 0.30
MCL1 Q07820 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
LPL P06858 1/20 0.30
LIPG Q9Y5X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18034448 0.89 MEN1 (0.33) PRMT5WDR77MEN1POLBMAPT
SCHEMBL18034407 0.89 MEN1 (0.33) PRMT5WDR77MEN1POLBMAPT
SCHEMBL18034401 0.89 MEN1 (0.33) PRMT5WDR77MEN1POLBMAPT
SCHEMBL20224582 0.89 MEN1 (0.32) PRMT5WDR77MEN1POLBMAPT
SCHEMBL19862392 0.87 PRMT5 (0.33) PRMT5WDR77LPLLIPG
SCHEMBL19862389 0.83 PRMT5 (0.32) PRMT5WDR77LPLLIPG
SCHEMBL19862383 0.83 PRMT5 (0.32) PRMT5WDR77LPLLIPG
SCHEMBL19869597 0.82 LPL (0.39) PRMT5WDR77LPLLIPG
SCHEMBL19863938 0.81 LPL (0.42) PRMT5WDR77LPLLIPG
SCHEMBL18034437 0.80 HIF1A (0.33) MEN1POLBMAPTDUSP3BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454039-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-10-22 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ORC3, AOX1, RCOR3 PRMT5 1822/4885WDR77 1593/4885MEN1 2797/4885
US-10454039-B2 Compound and organic electronic device using the same ORC3, AOX1, RCOR3 PRMT5 1822/4885WDR77 1593/4885MEN1 2797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.