SCHEMBL19862510

SCHEMBL19862510

Cc1cccc2c1sc1c(-c3cccc(-c4cncc(-c5cncc(-c6cccc(-c7cccc8c7sc7c(C)cccc78)c6)c5)c4)c3)cccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
MAP3K8 P41279 4/20 0.36
CYP17A1 P05093 1/20 0.36
CYP1A2 P05177 1/20 0.36
LIMK1 P53667 1/20 0.36
CYP2A6 P11509 2/20 0.35
TDO2 P48775 3/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
PDE10A Q9Y233 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16405902 1.00 ALOX5 (0.38) ALOX5MAP3K8CYP17A1CYP1A2LIMK1
SCHEMBL17032713 0.86 ALOX5 (0.43) ALOX5MAP3K8CYP17A1CYP1A2LIMK1
SCHEMBL16405904 0.86 LIMK1 (0.48) ALOX5MAP3K8CYP17A1CYP1A2LIMK1
SCHEMBL17032712 0.85 ALOX5 (0.46) ALOX5MAP3K8CYP17A1CYP1A2LIMK1
SCHEMBL16405939 0.82 ALOX5 (0.38) ALOX5MAP3K8LIMK1CYP11B2CYP2C9
SCHEMBL16405874 0.82 TDO2 (0.42) ALOX5CYP17A1CYP1A2LIMK1TDO2
SCHEMBL16405860 0.81 ALOX5 (0.58) ALOX5MAP3K8LIMK1MAPT
SCHEMBL16395346 0.81 ALOX5 (0.58) ALOX5MAP3K8LIMK1MAPT
SCHEMBL16405899 0.81 ALOX5 (0.58) ALOX5MAP3K8LIMK1MAPT
SCHEMBL29293140 0.80 MEN1 (0.49) CYP17A1CYP1A2LIMK1CYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047911-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-15 US disclosed
US-20180047911-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-15 US disclosed