SCHEMBL19862512

SCHEMBL19862512

Cc1ccc2sc3c(-c4cccc(-c5cncc(-c6cncc(-c7cccc(-c8cc(C)cc9c8sc8ccc(C)cc89)c7)c6)c5)c4)cc(C)cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP3K8 P41279 3/20 0.36
MAP2K4 P45985 1/20 0.35
ACLY P53396 2/20 0.32
ALOX5 P09917 1/20 0.32
PIM1 P11309 2/20 0.32
PIM2 Q9P1W9 2/20 0.32
SLC9A1 P19634 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PFKFB3 Q16875 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16405938 1.00 MAP3K8 (0.36) MAP3K8MAP2K4ACLYALOX5PIM1
SCHEMBL19862511 0.84 PSMB5 (0.35) MAP3K8MAP2K4ACLYCYP17A1
SCHEMBL16405903 0.84 PSMB5 (0.35) MAP3K8MAP2K4ACLYCYP17A1
SCHEMBL16405909 0.84 TGFBR1 (0.37) MAPTKDM4EMEN1ALDH1A1LMNA
SCHEMBL8281334 0.82 NPC1 (0.47) MAOAMAOBMAPTKDM4EMEN1
SCHEMBL16405917 0.80 MAP3K8 (0.45) MAP3K8ALOX5PIM1PIM2
SCHEMBL14554460 0.80 MAPT (0.34) ALOX5PIM1PIM2MAOAMAOB
SCHEMBL12268346 0.80 MAPT (0.33) ALOX5PIM1PIM2MAPTKDM4E
SCHEMBL4549309 0.80 CYP11B1 (0.37) ALOX5MAOAMAOBMAPTKDM4E
SCHEMBL10442470 0.79 ALOX5 (0.36) ALOX5PIM1PIM2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047911-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-15 US disclosed
US-20180047911-A1 Organic Compound, Light-Emitting Element, Display Module, Lighting Module, Light-Emitting Device, Display Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-15 US disclosed