SCHEMBL19862608

SCHEMBL19862608

c1ccc(-n2c3ccc(-c4cccc(-n5c6ccccc6c6ccc(-c7cccc(-n8c9ccccc9c9ccccc98)c7)cc65)c4)cc3c3ccncc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CDK4 P11802 3/20 0.39
CDK6 Q00534 3/20 0.39
DYRK1A Q13627 2/20 0.38
NPY5R Q15761 1/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HSP90AA1 P07900 1/20 0.36
GSK3B P49841 1/20 0.35
KCNH2 Q12809 1/20 0.35
PTGER4 P35408 1/20 0.34
CYP1A2 P05177 2/20 0.33
METAP2 P50579 2/20 0.33
TSPO P30536 1/20 0.33
IL1R1 P14778 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15945676 0.99 KDM4E (0.43) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL21481456 0.98 KDM4E (0.42) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL15945685 0.96 KDM4E (0.45) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL15945592 0.95 KDM4E (0.46) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL25919402 0.95 KDM4E (0.46) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL15945587 0.95 KDM4E (0.46) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL15945671 0.95 KDM4E (0.49) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL15945673 0.95 KDM4E (0.49) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL18958711 0.94 KDM4E (0.45) KDM4EATML3MBTL1CDK4CDK6
SCHEMBL17349259 0.94 KDM4E (0.45) KDM4EATML3MBTL1CDK4CDK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3269789-B1 LIGHT EMITTING MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-08-30 EP disclosed
US-10559761-B2 Light-emitting material, and organic electroluminescent device KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20180047915-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2018-02-15 US disclosed
US-20180047915-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047915-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE EML4, L1CAM, CRY1 KDM4E 3274/4885ATM 2814/4885L3MBTL1 320/4885
US-10559761-B2 Light-emitting material, and organic electroluminescent device EML4, L1CAM, CRY1 KDM4E 3274/4885ATM 2814/4885L3MBTL1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.