SCHEMBL19862658

SCHEMBL19862658

C=Cc1ccc(NC(=O)C(F)(F)S(=O)(=O)OC(C)C(=O)c2ccccc2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 5/20 0.41
ABCC8 Q09428 5/20 0.41
KCNJ11 Q14654 5/20 0.41
KCNJ8 Q15842 5/20 0.41
MCL1 Q07820 2/20 0.36
RECQL P46063 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGB1 P05556 1/20 0.34
ITGAV P06756 1/20 0.34
ITGA2B P08514 1/20 0.34
ITGB5 P18084 1/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19865868 0.89 ABCC9 (0.38) ABCC9ABCC8KCNJ11KCNJ8MCL1
SCHEMBL19862661 0.89 ABCC9 (0.44) ABCC9ABCC8KCNJ11KCNJ8MCL1
SCHEMBL19862659 0.85 KMT2A (0.39) ABCC9ABCC8KCNJ11KCNJ8NPC1
SCHEMBL19865867 0.79 ABCC9 (0.43) ABCC9ABCC8KCNJ11KCNJ8MCL1
SCHEMBL19862676 0.77 PDK1 (0.37) ABCC9ABCC8KCNJ11KCNJ8NPC1
SCHEMBL19862669 0.73 PDK1 (0.36) ABCC9ABCC8KCNJ11KCNJ8NPC1
SCHEMBL30739845 0.72 HDAC2 (0.56) ITGB3ITGB1ITGAVITGA2BITGB5
SCHEMBL10712444 0.70 MAPT (0.42) NPC1LMNARAB9AALDH1A1L3MBTL1
SCHEMBL19865204 0.70 MAPT (0.38) RECQLNPC1LMNARAB9AALDH1A1
SCHEMBL19862660 0.68 KMT2A (0.33) NPC1RAB9ASMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS CENTRAL GLASS CO., LTD. (JP) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS PPARG, PPARA, PPARD ABCC9 2303/4885ABCC8 2920/4885KCNJ11 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.