SCHEMBL15977823

SCHEMBL15977823

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4c5ccccc5c(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)c5cc(-c6ccc(-c7ccccn7)cn6)ccc45)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.44
PRMT5 O14744 2/20 0.34
DHODH Q02127 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
CNR2 P34972 1/20 0.34
WNT3A P56704 3/20 0.33
HPGDS O60760 1/20 0.33
AXL P30530 1/20 0.33
METAP2 P50579 1/20 0.33
CHEK2 O96017 1/20 0.33
KDR P35968 1/20 0.33
BACE1 P56817 1/20 0.32
CYP2A6 P11509 1/20 0.32
NPY5R Q15761 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977530 0.98 PDK2 (0.42) PDK2PRMT5DHODHWDR77CNR2
SCHEMBL15977810 0.94 PDK2 (0.39) PDK2DHODHHPGDSKDRALOX5AP
SCHEMBL15977727 0.93 PDK2 (0.47) PDK2PRMT5DHODHWDR77CNR2
SCHEMBL15977723 0.92 PDK2 (0.38) PDK2HPGDSKDRFEN1
SCHEMBL24810921 0.90 PDK2 (0.44) PDK2PRMT5DHODHWDR77
SCHEMBL19862729 0.89 PDK2 (0.41) PDK2DHODHCNR2HPGDSCHEK2
SCHEMBL15977928 0.88 PDK2 (0.39) PDK2DHODHKDRALOX5APFEN1
SCHEMBL26161307 0.88 PDK2 (0.36) PDK2HPGDSALOX5APFEN1
SCHEMBL15977831 0.88 PDK2 (0.43) PDK2DHODHCYP2A6
SCHEMBL15977575 0.87 PDK2 (0.42) PDK2CNR2HPGDSCHEK2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 PDK2 924/4885PRMT5 3653/4885DHODH 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.