SCHEMBL19863045

SCHEMBL19863045

c1ccc(-c2cc(-n3c4ccccc4c4c(-c5ccc6sc7ccccc7c6c5)cc5c6ccccc6oc5c43)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863071 0.93 MAPT (0.34) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL19863055 0.92
SCHEMBL19863021 0.90 MAPT (0.32) MAPTTSHR
SCHEMBL19863068 0.89 MAPT (0.37) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL19863049 0.89
SCHEMBL19863025 0.89 TSHR (0.31) MAPTTSHR
SCHEMBL18593780 0.88 MAPT (0.39) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL19863061 0.88 MAPT (0.39) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL18594353 0.87 MAPT (0.38) MAPTTSHRMAPK1NPSR1HSD17B10
SCHEMBL19862889 0.86 MAPT (0.35) MAPTTSHRMAPK1NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10230056-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2019-03-12 US disclosed
US-20180047914-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-15 US disclosed
US-20180047914-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10230056-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, NR2E3 MAPT 746/4885TSHR 3741/4885MAPK1 3622/4885
US-20180047914-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, NR2E3 MAPT 746/4885TSHR 3741/4885MAPK1 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.