SCHEMBL19863263

SCHEMBL19863263

CC(OS(=O)(=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)cc1)C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.61
CNR2 P34972 7/20 0.52
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
EPHX1 P07099 1/20 0.49
POLB P06746 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
ATM Q13315 2/20 0.47
PKM P14618 1/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
ALOX12 P18054 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19866808 0.85 FAAH (0.56) FAAHCNR2ALDH1A1LMNAEPHX1
SCHEMBL1421026 0.78 FAAH (1.00) FAAHCNR2ALDH1A1EPHX1POLB
SCHEMBL19863254 0.77 KMT2A (0.56) ALDH1A1LMNAKMT2AMEN1KDM4E
SCHEMBL19862494 0.76 FAAH (0.48) FAAHCNR2ALDH1A1LMNAEPHX1
SCHEMBL10709364 0.75 KMT2A (0.48) ALDH1A1LMNAKMT2AKDM4EMAPT
SCHEMBL19857282 0.73 CNR2 (0.66) FAAHCNR2ALDH1A1LMNAPOLB
SCHEMBL3096091 0.73 RECQL (0.49) ALDH1A1LMNAKMT2AMEN1TSHR
SCHEMBL22308141 0.73 FAAH (0.82) FAAHCNR2ALDH1A1EPHX1POLB
SCHEMBL10710904 0.72 FLT1 (0.48) ALDH1A1KMT2AMEN1ATMMAPT
SCHEMBL4934547 0.72 FAAH (0.85) FAAHCNR2ALDH1A1EPHX1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG FAAH 26/4885CNR2 3083/4885ALDH1A1 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.