Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863499 | 0.99 | PPARA (0.42) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19863498 | 0.96 | PPARA (0.44) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL12445350 | 0.96 | PPARA (0.44) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19870995 | 0.96 | PPARA (0.44) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19870993 | 0.94 | PPARA (0.46) | KMT2APPARAMAPTGAAESR1 | |
| SCHEMBL19870998 | 0.93 | KMT2A (0.41) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19870999 | 0.92 | PPARA (0.41) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19863501 | 0.92 | PPARA (0.41) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19870994 | 0.92 | PPARA (0.41) | KMT2APPARAMAPTGAAHPGD | |
| SCHEMBL19863497 | 0.91 | RARA (0.43) | KMT2APPARAMAPTGAAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180046101-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20180046100-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |