Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983557 | 0.90 | MAPT (0.38) | CNR1MAPTTP53GAAKMT2A | |
| SCHEMBL1986855 | 0.89 | CNR1 (0.41) | CNR1CNR2MAPTTP53GAA | |
| SCHEMBL1985549 | 0.88 | MAPT (0.40) | MAPTTP53GAAKMT2ASMN1; SMN2 | |
| SCHEMBL1988695 | 0.86 | CNR1 (0.45) | CNR1CNR2MAPTTP53GAA | |
| SCHEMBL1984047 | 0.85 | CNR2 (0.59) | CNR1CNR2LMNA | |
| SCHEMBL1983442 | 0.83 | MAPT (0.37) | CNR1MAPTTP53GAAKMT2A | |
| SCHEMBL1985398 | 0.83 | CNR1 (0.51) | CNR1CNR2MAPTGAAKMT2A | |
| SCHEMBL1985554 | 0.81 | MAPT (0.39) | CNR1MAPTTP53GAAKMT2A | |
| SCHEMBL1986572 | 0.80 | SMN1; SMN2 (0.39) | CNR1MAPTTP53GAAKMT2A | |
| SCHEMBL1983811 | 0.79 | MAPT (0.40) | MAPTTP53KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |