Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985554 | 0.92 | MAPT (0.39) | SMN1; SMN2PPP1CAMAPTTP53GAA | |
| SCHEMBL1983442 | 0.90 | MAPT (0.37) | SMN1; SMN2PPP1CAMAPTTP53GAA | |
| SCHEMBL1984758 | 0.88 | MAPT (0.40) | SMN1; SMN2MAPTTP53KMT2AMEN1 | |
| SCHEMBL1989244 | 0.87 | KMT2A (0.37) | SMN1; SMN2PPP1CAMAPTTP53GAA | |
| SCHEMBL1987373 | 0.86 | CNR2 (0.43) | LMNACNR1 | |
| SCHEMBL1985425 | 0.84 | MALT1 (0.40) | SMN1; SMN2MAPTKMT2AMALT1LMNA | |
| SCHEMBL1986571 | 0.83 | CYP1A2 (0.46) | SMN1; SMN2PPP1CAMAPTGAAMALT1 | |
| SCHEMBL1983557 | 0.83 | MAPT (0.38) | SMN1; SMN2PPP1CAMAPTTP53GAA | |
| SCHEMBL1986855 | 0.82 | CNR1 (0.41) | SMN1; SMN2PPP1CAMAPTTP53GAA | |
| SCHEMBL1986352 | 0.80 | CNR1 (0.42) | SMN1; SMN2PPP1CAMAPTTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |