Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863811 | 0.96 | SIRT2 (0.41) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19869442 | 0.94 | SIRT2 (0.38) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19863833 | 0.94 | SIRT2 (0.41) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19869438 | 0.92 | SIRT2 (0.37) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19869499 | 0.92 | SIRT2 (0.38) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19863880 | 0.92 | ESR1 (0.44) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19869428 | 0.89 | SIRT2 (0.36) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19164070 | 0.88 | ESR1 (0.43) | SIRT2SIRT1ESR1ESR2HCAR1 | |
| SCHEMBL19862215 | 0.88 | SIRT2 (0.34) | SIRT2SIRT1ESR1ESR2PTGER4 | |
| SCHEMBL19869463 | 0.88 | SIRT2 (0.36) | SIRT2SIRT1ESR1ESR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| EP-3281936-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | Nichem Fine Technology Co., Ltd. (TW) | 2018-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | SIRT2 2055/4885SIRT1 3275/4885ESR1 1/4885 |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | ESR1, AOC2, PIEZO1 | SIRT2 2055/4885SIRT1 3275/4885ESR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.