Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23081207 | 0.89 | HPGD (0.42) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL11890370 | 0.86 | RAB9A (0.54) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL24973934 | 0.84 | RAB9A (0.38) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL23634150 | 0.84 | RAB9A (0.38) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL557178 | 0.84 | HPGD (0.41) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL556705 | 0.84 | CA12 (0.40) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL11890375 | 0.82 | RAB9A (0.58) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL20072359 | 0.82 | RAB9A (0.42) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL23841163 | 0.81 | RAB9A (0.41) | RAB9AHPGDCYP3A4CYP2C19EPHX1 | |
| SCHEMBL8241745 | 0.80 | EPHX1 (0.58) | RAB9AHPGDCYP3A4CYP2C19EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198031-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | Merck Patent GmbH (DE) | 2023-06-21 | — | — | EP | disclosed |
| WO-2018031434-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-02-15 | — | — | WO | disclosed |