SCHEMBL20072359

SCHEMBL20072359

CC(=O)C1CCCC(NC(=O)CC(C)C)C1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.42
HPGD P15428 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
EPHX1 P07099 2/20 0.38
KMT2A Q03164 3/20 0.38
BTK Q06187 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM5A P29375 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GAA P10253 1/20 0.36
PREP P48147 1/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23841163 0.86 RAB9A (0.41) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL11890370 0.84 RAB9A (0.54) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL19864588 0.82 RAB9A (0.43) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL11890375 0.81 RAB9A (0.58) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL8241745 0.79 EPHX1 (0.58) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL18199497 0.77 RAB9A (0.49) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL5067337 0.77 RAB9A (0.49) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL18199502 0.77 RAB9A (0.41) RAB9AHPGDCYP3A4CYP2C19EPHX1
SCHEMBL23826543 0.75 BTK (0.47) RAB9ACYP3A4EPHX1KMT2ABTK
SCHEMBL23826924 0.75 BTK (0.47) RAB9ACYP3A4EPHX1KMT2ABTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526239-B1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-11-03 EP disclosed
US-11162104-B2 SCN9A antisense pain killer OLIPASS CORPORATION (KR) 2021-11-02 US disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
US-20190218255-A1 SCN9A ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-07-18 US disclosed
WO-2018069764-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 RAB9A 4668/4885HPGD 4203/4885CYP3A4 2758/4885
US-20190218255-A1 SCN9A ANTISENSE OLIGONUCLEOTIDES SCN9A, SCN7A, SCN8A RAB9A 434/4885HPGD 4694/4885CYP3A4 4222/4885
US-11162104-B2 SCN9A antisense pain killer SCN9A, SCN7A, SCN8A RAB9A 409/4885HPGD 4549/4885CYP3A4 3111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.