Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10260946 | 0.88 | HDAC6 (0.40) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL19865534 | 0.87 | CHRNB2 (0.37) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL1455952 | 0.85 | MVD (0.38) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL18257000 | 0.85 | CA14 (0.42) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL21871862 | 0.85 | GBA1 (0.35) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL25479216 | 0.85 | CA14 (0.42) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL7783463 | 0.85 | HDAC6 (0.38) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL25129557 | 0.84 | MVD (0.37) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL25970378 | 0.83 | CA14 (0.40) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL17337834 | 0.82 | GBA1 (0.36) | GBA1HDAC6CA14HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10682418-B2 | Polymer-sunitinib conjugates | NEKTAR THERAPEUTICS (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180043028-A1 | POLYMER-SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180043028-A1 | POLYMER-SUNITINIB CONJUGATES | FLT4, TEK, TIE1 | GBA1 2931/4885HDAC6 310/4885CA14 1889/4885 |
| US-10682418-B2 | Polymer-sunitinib conjugates | FLT4, TEK, TIE1 | GBA1 2931/4885HDAC6 310/4885CA14 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.