SCHEMBL1455952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25129557	0.98	MVD (0.37)	MVDGBA1CA14PDK2BHMT
	SCHEMBL19865535	0.85	GBA1 (0.35)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL10260946	0.84	HDAC6 (0.40)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL336495	0.83	HDAC6 (0.37)	MVDGBA1CA14PDK2HDAC6
	SCHEMBL18257000	0.81	CA14 (0.42)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL21871862	0.81	GBA1 (0.35)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL25479216	0.81	CA14 (0.42)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL7783463	0.81	HDAC6 (0.38)	GBA1CA14PDK2HDAC6HDAC1
	SCHEMBL20762898	0.81	GBA1 (0.39)	GBA1CA14PDK2HDAC6HDAC1
	Ammonia Solution, Strong SCHEMBL29062672	0.81	HDAC6 (0.36)	MVDGBA1CA14PDK2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.