Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574013 | 0.84 | CYP1A2 (0.61) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL30201139 | 0.84 | CYP1A2 (0.61) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL14214472 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL19079581 | 0.81 | HRH1 (0.53) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL29485678 | 0.81 | HRH1 (0.73) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL230753 | 0.81 | HRH1 (0.73) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL8662285 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL10771160 | 0.81 | HRH1 (0.57) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL6938906 | 0.81 | HRH1 (0.57) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 | |
| SCHEMBL23765410 | 0.80 | GRIN2D (0.52) | CYP1A2ALDH1A1CYP2C19HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | PDE3A, PDE2A, PDE5A | CYP1A2 677/4885ALDH1A1 436/4885CYP2C19 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.