Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923055 | 0.78 | MAPK1 (0.43) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL9818052 | 0.71 | KMT2A (0.73) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL12337250 | 0.70 | HSD17B10 (0.34) | HSD17B10 | |
| SCHEMBL12337617 | 0.70 | — | — | |
| SCHEMBL378134 | 0.68 | KMT2A (0.61) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL11424105 | 0.67 | HSD17B10 (0.74) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL17457887 | 0.67 | HSD17B10 (0.74) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| Hydrochloric Acid SCHEMBL7400678 | 0.67 | KMT2A (0.59) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL1483217 | 0.66 | KMT2A (0.64) | KMT2AHSD17B10LMNAMMP12MMP13 | |
| SCHEMBL14330470 | 0.66 | KMT2A (0.64) | KMT2AHSD17B10LMNAMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092222-B1 | IMPROVED FINGOLIMOD PROCESS | EMCURE PHARMACEUTICALS LTD (IN) | 2018-02-14 | — | — | EP | disclosed |