SCHEMBL1483217

SCHEMBL1483217

CCCc1ccc(C(C)=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
PLK1 P53350 2/20 0.62
THRB P10828 3/20 0.60
HSD17B10 Q99714 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.58
LMNA P02545 2/20 0.55
POLB P06746 3/20 0.55
CTDSP1 Q9GZU7 3/20 0.55
ALDH1A1 P00352 3/20 0.55
GAA P10253 2/20 0.55
KDM4E B2RXH2 1/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAPT P10636 1/20 0.53
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
THRA P10827 2/20 0.49
MMP12 P39900 1/20 0.49
MMP13 P45452 1/20 0.49
RARB P10826 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9406602 0.94 RARB (0.58) KMT2APLK1THRBHSD17B10L3MBTL1
SCHEMBL25175254 0.89 MAPT (0.68) KMT2APLK1THRBHSD17B10L3MBTL1
SCHEMBL9818052 0.88 KMT2A (0.73) KMT2APLK1HSD17B10L3MBTL1LMNA
SCHEMBL967078 0.87 HSD17B10 (0.67) KMT2APLK1THRBHSD17B10POLB
SCHEMBL18477943 0.86 L3MBTL1 (0.66) KMT2AL3MBTL1LMNAPOLBALDH1A1
SCHEMBL4122562 0.86 MAPT (0.62) KMT2APLK1LMNAPOLBALDH1A1
SCHEMBL963847 0.85 THRA (0.67) KMT2ATHRBHSD17B10ALDH1A1MAPT
SCHEMBL5339874 0.84 TRPV1 (0.61) KMT2APLK1LMNAPOLBCTDSP1
SCHEMBL11424105 0.84 HSD17B10 (0.74) KMT2APLK1THRBHSD17B10L3MBTL1
SCHEMBL17457887 0.84 HSD17B10 (0.74) KMT2ATHRBHSD17B10L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN claimed
CN-117304135-A Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative 衡阳师范学院 2023-12-29 CN claimed
CN-116178365-A Berberine hydrochloride derivative and preparation method and application thereof 常州大学 2023-05-30 CN claimed
CN-114276308-A Magnetic resonance contrast agent and preparation method and application thereof 南京科技职业学院 2022-04-05 CN claimed
CN-119930469-A Chalcone compound containing alpha, beta-unsaturated hydroxamic acid groups and preparation method and application thereof 河北医科大学 2025-05-06 CN disclosed
CN-116178365-B Berberine hydrochloride derivative and preparation method and application thereof 常州大学 2025-04-08 CN disclosed
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN disclosed
CN-118546054-A Method for preparing alpha-deuterated ketone compound by photocatalysis and application thereof 武汉大学 2024-08-27 CN disclosed
CN-112218844-B Compound, resin, composition, resist pattern forming method, circuit pattern forming method, and resin purifying method 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
CN-115968391-B Composition, resin, method for producing amorphous film, method for forming resist pattern, method for producing underlayer film for lithography, and method for forming circuit pattern 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
CN-115975695-B Lubricating oil composition capable of realizing wide Wen Yuchao sliding 武汉理工大学 2024-04-16 CN disclosed
US-20240117101-A1 COMPOSITION FOR FILM FORMATION, RESIST COMPOSITION, RADIATION-SENSITIVE COMPOSITION, METHOD FOR PRODUCING AMORPHOUS FILM, RESIST PATTERN FORMATION METHOD, COMPOSITION FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY, METHOD FOR PRODUCING UNDERLAYER FILM FOR LITHOGRAPHY, CIRCUIT PATTERN FORMATION METHOD, COMPOSITION FOR OPTICAL MEMBER FORMATION, RESIN FOR UNDERLAYER FILM FORMATION, RESIST RESIN, RADIATION-SENSITIVE RESIN, AND RESIN FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-11 US disclosed
CN-86105663-A Compound 1987-01-21 CN disclosed
EP-0208517-A2 6-Oxo-pyridazinyl compounds SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1987-01-14 EP disclosed
EP-0170082-A2 Liquid crystalline isothiocyanates with a dioxane ring and liquid crystalline admixtures containing the same Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) 1986-02-05 EP disclosed
EP-0136480-A2 2,3-Dicyano-5-substituted pyrazines and liquid crystal composition containing them Chisso Corporation (JP) 1985-04-10 EP disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed
US-4261651-A CYCLOHEXANE CONTAINING DERIVATIVES OF AROMATIC NITRILES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1981-04-14 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed