SCHEMBL19867174

SCHEMBL19867174

CNN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(O)O)C(=O)O)C(=O)O)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.58
▸ CCKAR P32238 10/20 0.43
▸ CCKBR P32239 10/20 0.43
▸ FOLH1 Q04609 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19867250 0.94 GLP1R (0.64) GLP1RCCKARCCKBRFOLH1
SCHEMBL19867199 0.94 GLP1R (0.64) GLP1RCCKARCCKBRFOLH1
SCHEMBL21100103 0.90 GLP1R (0.60) GLP1RCCKARCCKBRFOLH1
SCHEMBL14819894 0.87 GLP1R (0.68) GLP1RCCKARCCKBR
SCHEMBL21172414 0.86 GLP1R (0.59) GLP1RCCKARCCKBRFOLH1
SCHEMBL13577532 0.86 GLP1R (0.69) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099729 0.85 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL21099731 0.85 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL16192884 0.85 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1
SCHEMBL19867247 0.85 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK AS (DK) 2018-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE GLP1R, GIPR, GCGR GLP1R 1/4885CCKAR 24/4885CCKBR 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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