Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.47 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29677914 | 0.91 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL31376514 | 0.91 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL22339734 | 0.91 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL9951429 | 0.91 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL22339325 | 0.90 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL22339742 | 0.90 | MAPT (0.55) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL22339748 | 0.90 | KDR (0.50) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL18804926 | 0.90 | RXFP1 (0.49) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL22339751 | 0.88 | RXFP1 (0.48) | UTS2RLMNAMAPTMEN1KMT2A | |
| SCHEMBL9952083 | 0.87 | RXFP1 (0.50) | UTS2RLMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654428-B1 | HISTONE ACETYLTRANSFERASE MODULATORS AND USESE THEREOF | UNIV COLUMBIA (US) | 2018-02-14 | — | — | EP | disclosed |