Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22339734 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL29677914 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL9951429 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL31376514 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL18804926 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL22339742 | 0.90 | MAPT (0.55) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL22339325 | 0.90 | RXFP1 (0.49) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL19868331 | 0.90 | UTS2R (0.52) | KDRRXFP1LMNAGAAMAPT | |
| SCHEMBL22339747 | 0.89 | LMNA (0.52) | KDRLMNAGAAMAPTRAB9A | |
| SCHEMBL22339751 | 0.89 | RXFP1 (0.48) | KDRRXFP1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127232-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF | APPIA PHARMACEUTICALS LLC | 2022-04-28 | — | — | US | disclosed |
| WO-2020163731-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127232-A1 | HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF | EP300, KAT2A, NAA40 | KDR 4837/4885RXFP1 4617/4885LMNA 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.