Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | ITGAL | P20701 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096294 | 0.85 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL8675912 | 0.83 | ECE1 (0.42) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL2514366 | 0.83 | ECE1 (0.42) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1986931 | 0.81 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL1986933 | 0.81 | ECE1 (0.43) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL4397483 | 0.81 | KMT2A (0.44) | CA2CA1KMT2ATGFBR1 | |
| SCHEMBL9192330 | 0.78 | MEN1 (0.48) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL21964217 | 0.77 | ECE1 (0.41) | ECE1ITGB2ICAM1ITGALCA2 | |
| Asparagine SCHEMBL8015948 | 0.77 | ALOX15 (0.39) | ECE1ITGB2ICAM1ITGALCA2 | |
| SCHEMBL88481 | 0.75 | ECE1 (0.46) | ECE1ITGB2ICAM1ITGALCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042538-A1 | Amphiphilic copolymers and compositions containing such polymers | Nirvana's Tree House (NL) | 2009-04-01 | — | — | EP | claimed |
| EP-2042538-A1 | Amphiphilic copolymers and compositions containing such polymers | Nirvana's Tree House (NL) | 2009-04-01 | — | — | EP | disclosed |